Searchable abstracts of presentations at key conferences in endocrinology

ea0013p272 | Steroids | SFEBES2007

A central physiological role for attenuated circulating DHEAS levels in aged female Rhesus Macaques?

Urbanski Henryk , Lemos Dario , Sitzmann Brandon , Garyfallou Vasilios , Kohama Steven

In humans and rhesus monkeys (Macaca mulatta) the zona reticularis of the adrenal gland produces large amounts of dehydoepiandrosterone (DHEA) and its sulfated form, DHEAS. The circulating levels of these steroids are particularly high during early adulthood, and they then decline gradually during aging, especially in females. To help elucidate the physiological function of this steroidal loss we examined the 24-hour plasma profiles of DHEAS in female rhesus monkeys, us...